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1) Sperm Induction of acrosome reaction in spermatozoa accelates development of fertilized human oocyte after intracytoplasmic sperm injection. (52th ASRM, 1996).Identification of round spermatid from testis biopsy and its application in human ART program. (10th World Congress on IVF & ART, 1997) Detailed semen analysis and ICSI in azoospermia-like infertile patients. (53th ASRM, 1997)
2) AZF and Microdeletion Microdeletions of Y Chromosome in Korean Male Infertility Patients (5th ICA,1997) Evaluation of spermatogenesis by DAZ and protamine-2 gene in human testis biopsy (5th ICA, 1997) The Incidence of microdeletion and the frequency of AZFa, b, c deletion in male infertility patients. (53th ASRM, 1997)
3) ART Application of ICSI or ROSI by testicular biopsy in non-obstructive azoospermia.(53th ASRM, 1997) Analysis of fertilization, embryonic development and pregnancy rates after ICSI using spermatozoa obtained from fresh or frozen-thawed testicular tissues (54th ASRM, 1998)
1) Oocytes Production of mature oocyte from frozen-thawed primordial follicular oocyte by reconstruction with cytoplasm of full grown germinal vesicle(GV)-stage oocyte. (55th ASRM, 1999)
2) Follicle In vitro Growth of Primordial Follicular Oocyte in the Frozen-Thawed Ovarian Tissue of Neonatal Mouse (54th ASRM, 1998) Steroidogenesis in the Frozen-Thawed 18 Weeks Human Fetal Ovarian Tissues Cultured In Vitro (54th ASRM, 1998) TGF ¥âI and TGF ¥âII were detected from fresh 18 weeks fetal ovarian tissue in human.
3) Ovarian Endocrinology Expression of Melatonin receptor gene in mouse gonad. (54th ASRM, 1998) The synergistic effect of VIP and FSH in vitro on the expression of FSH receptor gene in human fetal ovary. (55th ASRM, 1999) Expression of receptor genes for gonadotrophins and estrogens, and biosynthesis of estrogen in mid-gestational stage of human ovarian tissues. (55th ASRM, 1999) Expression and localization of cell cycle-related proteins and receptor genes for gonadotropins, estrogen, and aromatase in human fetal ovaries; a preliminary study (International Workshop on Early Folliculogenesis and Oocyte Development,1999) The effect of vasoactive intestinal peptide on estradiol biosynthesis in human fetal ovarian tissue in vitro.(International Workshop on Early Folliculogenesis and Oocyte Development 1999)
1) Embryology Regulation of embryonic genome activation and compaction by the transfer of cytoplasm transfer with inhibitors of protein synthesis or protein kinase in mouse. (32th SSR, 1999)
2) Hatching Biochemical Assisted Hatching by Proteases Increased Pregnancy Rates in Human IVF-ET Program (1996' ASRM) Application of biochemically assisted hatching(BAH) by proteases in human assisted reproductive technology program. (53th ASRM, 1997) Improvement of pregnancy and implantation rate by biochemical assisted hatching in human IVF-ET. (11th World Congress on IVF & Hum Reprod Genet, 1999) Outcome of Biochemical Assisted Hatching in 1068 IVF-ET Cycles Using Pronase in Human Assisted Reproductive Technology. (11th World Congress on IVF & Hum Reprod Genet, 1999) Biochemical assisted hatching(BAH) increased the implantation and pregnancy rate in human cryopreserved embryo transfer. (55h ASRM, 1999)
3) Implantation Regulation of integrin a1, av, and b3 gene expression by leukemia inhibitory factor(LIF) during blastocyst outgrowth in the mouse.(30th SSR, 1997)
1) Hatching and outgrowth according to various freezing procedures in mouse blastocyst cryopreservation. (12th ESHRE, 1996)
2) Pregnancy from Translocation carrier patient with recurrent abortion by preimplantation genetic diagnosis using fluorescence in-situ hybridization. (52th ASRM, 1996)
3) Assisted Reproductive Technology Program by Immature Oocyte Retrieval in Non-stimulated Cycle (54th ASRM, 1998)
4) Clincial use of immature oocyte from normal and PCO women in non-stimulated IVF-ET program. (55th ASRM, 1999)
1) Effect of the antioxidant supplemented into semen or sperm washing medium on functional parameter of human spermatozoa (KSFS 2006)
2) Correlation between seminal parameter of patients and sperm DNA fragmentation estimated by comet assay (KSFS 2006)
A). Adult stem cells
  (1) In vitro proliferation and differentiation of placenta derived cell and HSC isolated from umbilical cord blood
  (2) Effect of oxygen tension and antioxidant on proliferation of HSC in vitro
B) Embryonic stem cells
  (1) Establishment of gene knock-in system in hES cells
  (2) Single cell culture of hES cells
  (3) Differentiation of hES cells into germ cells
A). Cytogenetics
  (1) Amniotic fluid
  (2) Chorionic villi cells
  (3) Peripheral blood / Cord blood
  (4) Tissue
B) Molecular genetics
  (1) Preimplantation genetic diagnosis (PGD, FISH)
  (2) Preimplantation genetic screening (PGS, FISH)
  (3) Azoospermia related gene test (Daz test)
  (4) Amniotic fluid FISH (18, 21)
 
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